Welcome to The Chemical Synthesis Group

Development of New Synthetic Methods

Total Synthesis of Complex Natural Products

Discovery of Novel Anibiotics

Our Research


Natural Products

Synthetic Methods

Drug Discovery

Group Members

our Publications

[14] Senthil Kumar, S.; Valdomir, G.; Ganapathy, D.; Zhang, Y.; Lutz F. Tietze. Enantioselective Total Synthesis of the Fungal Metabolite Blennolide D and the Enantiomers of Blennolide E and F. Org. Lett. 2018,20, 2186–2189.
[13] Valdomir, G.; Senthil Kumar, S.; Ganapathy, D.; Zhang, Y.; Lutz F. Tietze. Enantioselective Total Synthesis of Blennolide H and Phomopsis‐H76 A and Determination of Their Structure. Chem. Eur. J. 2018, 24, 8760-8763.
[12] Senthil Kumar, S.; Valdomir, G.; Ganapathy, D.; zhangyun, Lutz F. Tietze. Enantioselective Total Synthesis of Chromanone Lactone Homo- and Heterodimers. Chem. Asian. J. 2018,13, 1888-18891.
[11] Ganapathy, D.; Reiner, J. R.; Valdomir, G.; Senthil Kumar, S.; Lutz F. Tietze. Enantioselective Total Synthesis and Structure Confirmation of the Natural Dimeric Tetrahydroxanthenone Dicerandrol C. Chem. Eur. J.2017, 23,2290 –2302.
[10] Tietze, L.F.; Jackenkroll, S.; Ganapathy, D.; Reiner, J. R. Tietze. Formal Synthesis of (–)-Siccanin Using an Enantioselective Domino Wacker/Carbonylation/Methoxylation Reaction. Synlett 2016, 27, 96-100.
[09] Ganapathy, D.; Reiner, J. R.; Loeffler, L. E.; Ma, L.; Gnanaprakasam, B.; Niepoetter, B.; Koehne, I.; Lutz F. Tietze. Enantioselective Total Synthesis of Secalonic Acid E. Chem. Eur. J 2015, 21,16807 –16810.
[08] Tietze, L.F.; Waldecker, B.; Ganapathy, D.; Eichhorst, C.; Lenzer, T.; Oum, K.; Reichmann, S. O.; Stalke, D. Four- and Sixfold Tandem-Domino Reactions Leading to Dimeric Tetrasubstituted Alkenes Suitable as Molecular Switches. Angew. Chem. Int. Ed. 2015, 54, 10317 –103210.
[07] Ganapathy, D.; Sekar. G. Stable palladium nanoparticles catalyzed synthesis of benzonitriles using K4[Fe(CN)6]. Tetrahedron Lett. 2015, 2015, 56, 175-178.
[06] Ganapathy, D.; Sekar. G. Efficient Synthesis of Polysubstituted Olefins Using Stable Palladium Nanocatalyst: Applications in Synthesis of Tamoxifen and Isocombretastatin A4. Tetrahedron Lett. 2015, 2015, 56, 175-178.
[05] Sindhura, B.; Ganapathy, D.; Ankita, D.; Singh, R.; Sekar, G. FeCl2-BINAM complex catalyzed domino synthesis of bisindolylmethanes from indoles and primary alcohols. Synthesis 2014, 46, 0101–0109..
[04] Ganapathy, D.; Sekar. G. Palladium nanoparticles stabilized by metal–carbon covalent bond: An efficient and reusable nanocatalyst in cross-coupling reactions. Catal. Commun. 2013, 39, 50-54..
[03] Alamsetti, S. K.; Ganapathy, D.; Sekar, G. Enantioselective Oxidative Coupling of 2-Naphthol Derivatives by Copper-(R)-1,1'-Binaphthyl-2,2'-diamine-TEMPO Catalyst. Adv. Synth. Catal. 2013, 355, 2803-2808..
[02] Thakur, K. G.; Ganapathy, D.; Sekar. G. D-Glucosamine as a green ligand for copper catalyzed synthesis of primary aryl amines from aryl halides and ammonia. Chem. Commun. 2011, 47, 5076–5078..
[01] Naidu A. B. Ganapathy, D.; Sekar, G. Copper(I)-Catalyzed Intramolecular Caryl–O Bond-Forming Cyclization for the Synthesis of 1,4-Benzodioxines and Its Application in the Total Synthesis of Sweetening Isovanillins. Synthesis 2010, 20, 3509–3519.

Open Positions

Doctoral Researcher:
Candidates with M.Sc. degree are currently invited to apply through the IIT Bhilai website (https://www.iitbhilai.ac.in/index.php?pid=adm_phd_new) for the advertisement for the Ph.D. program (2020-21-M session). Students joining in our group will have the opportunity to gain expertise in synthetic organic chemistry, catalysis, total synthesis of natural products and antibiotics development. Priority will be given to the candidates having fellowship (INSPIRE/CSIR-JRF/GATE). Institute will provide funding opportunities for outstanding candidates. Those who are joining for the PhD program have to complete their course work during their first year.
Postdoctoral Researcher:
We are currently looking for talented and highly motivated PhD students and postdoctoral scientists. Applicants for the postdoctoral position should possess a PhD in synthetic chemistry, organic chemistry, catalysis, antibiotics or a related field. Currently there are no funded positions available. Candidates interested to apply for a fellowship are encouraged to apply by sending a cover letter, CV, relevant publications, and contact information to Dr. Ganapahty by email (ganapathy@iitbhilai.ac.in), please visit IIT Bhilai website (https://www.iitbhilai.ac.in/index.php?pid=rec_staff) for latest openings and updates.

contact us

Dr. Ganapathy
Assistant Professor,
Department of Chemistry, Indian Institute of Technology Bhilai, GEC Campus, Sejbahar, Raipur - 492 015 chhattisgarh, India
e-mail: ganapathy@iitbhilai.ac.in Ph: +91-771-255-1300; Extn: 6158